IVF
with ROPA method

 

 

 

IVF-ROPA (Reception of Oocytes from Partner) is an assisted reproductive treatment designed for female or transgender couples with female genitalia, allowing both partners to participate in the reproductive process.

One of them undergoes ovarian stimulation to retrieve her eggs, which are then fertilised with donor sperm.

Then, after preparing the uterus, the other person receives one of the resulting embryos to carry the pregnancy forward.

IVF-ROPA is a treatment very similar to IVF with donated oocytes, but in this case, it is a donation process within a couple. This requires that the person donating the oocytes has ovaries and the person receiving the embryo has a uterus.

The person who donates the eggs undergoes a process of ovarian stimulation according to their characteristics and, after follicular puncture and oocyte retrieval, these are fertilised with a seminal sample from a sperm donor.

The gestational carrier must undergo endometrial preparation, again according to her characteristics, so that the embryo transfer can take place at the ideal moment for the embryo to implant. 

Endometrial preparation can be synchronous, i.e. the gestational carrier prepares to receive a fresh embryo after the follicular puncture of the partner, or it can be asynchronous. In this case, on the one hand, the embryos are generated in the first stage and frozen, and on the other hand, in a second stage, the gestational carrier performs the endometrial preparation to receive a cryopreserved embryo. 

Other particularities such as the indication to perform a genetic diagnosis of the embryos prior to the embryo transfer (IVF PGT-A) will be determined by the characteristics of the couple at the time of the treatment and not so much by the IVF-ROPA technique itself.

STAGES OF THE PROCEDURE
01 Previous Tests

Tests that the doctor deems appropriate must be completed before treatment can begin. These are usually blood tests and transvaginal ultrasound of both partners. 

02 Procedure

Treatment preparation visit: Organisation and explanation of the cycle, resolution of doubts and medication schedule for ovarian stimulation.

Ovarian stimulation: For about 10-12 days, the person providing the oocytes must take the prescribed medication and attend the necessary ultrasound checks in order to obtain the maximum number of oocytes in that cycle.

Ovarian puncture: Removal of eggs under sedation.

Embryo generation: In vitro fertilisation of oocytes with donor semen sample and embryo culture until the blastocyst stage.

Endometrial preparation: Preparation of the endometrium for the transfer begins with the menstrual period and will require several gynaecological ultrasound scans. Medication may be required and will be indicated by the doctor.

Embryo transfer: Once the endometrium is prepared, the embryo transfer is performed. During a transabdominal ultrasound-guided procedure, the embryo is positioned in the most suitable place in the uterus for implantation.

Procedure
03 Gestational Control

Pregnancy test: Approximately 11 days after the transfer, a blood draw is performed for a pregnancy test.

Confirmation ultrasound: If the pregnancy test is positive, an ultrasound scan is performed after 2 weeks to assess the pregnancy and confirm that it is developing correctly.

IVF-ROPA (Partner Oocyte Reception) is an assisted reproductive treatment designed for female or transgender couples with female genitalia, allowing both to participate in the reproductive process.

 

WHO IS IT FOR?

  • In order to be able to perform IVF-ROPA, the person who is going to donate the oocytes must have ovaries and the person who receives the embryo must have a uterus.
  • That is why this treatment can be offered to couples of cis women or to couples in which one or both members are trans men with preserved internal genitalia for the role they wish to carry in the treatment.

SUCCESS RATES

It has a similar success rate to IVF and depends largely on the age of the woman donating the eggs and the characteristics of the uterus that will receive the embryos generated. 

The average success rate is 45-55% per transfer. This rate increases if a genetic study of the embryos is performed prior to the transfer (PGT-A IVF). The doctor will advise you if this is necessary.

FAQs

No legal partnership is required for IVF-ROPA treatment. The signature of an informed consent for the treatment by both partners confers them parental authority over the embryos obtained.

The sperm donor is selected from a sperm bank. The choice is made based on the recipient’s physical characteristics, blood type and other factors such as genetic matching. Donors undergo rigorous medical, psychological and genetic screening.

 

es, you can lead a normal life during treatment, except for a few days before and after the puncture. You cannot have sexual relations or engage in high-intensity physical exercise. Ovarian stimulation is a treatment that is very well tolerated by patients. During this process, you may experience abdominal distension, breast turgor and/or a certain degree of tiredness. On the day of the egg retrieval (ovarian puncture) you will need to rest and will not be able to work.

No, ultra-rapid freezing techniques (vitrification) carried out by expert professionals allow a survival rate of 98-99% after thawing, so frozen embryos have a high probability of success.

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