Artificial Insemination with Donor Semen

 

 

 

 

 

Artificial insemination with donor sperm (AIS) is an assisted reproduction procedure in which donor sperm is introduced into the woman’s uterus to facilitate fertilisation of the egg. 

This procedure is ideal for women facing single motherhood, couples of women or heterosexual couples where the man has severe fertility problems and we must resort to donor sperm.

STAGES OF THE PROCEDURE
01 Previous Tests

Medical consultation: Assessment of the woman or couple to determine suitability of treatment.

Diagnostic tests: Ultrasound with evaluation of ovarian reserve and blood tests. In some cases, hysterosalpingography or hysterosonography may be recommended.

02 Procedure

Donor selection: An anonymous donor is chosen based on the physical characteristics and blood type of the woman or couple. Donors are rigorously screened and tested for general physical health, psychological health, genetics and infectious diseases. There is the possibility of genetic matching between donor and recipient by means of a cross-matching test for carriers of recessive genetic diseases. 

Ovarian Preparation and Stimulation: To determine the ideal moment for insemination, we must monitor the cycle by means of ultrasound scans to evaluate follicular development. In some cases we will also order blood tests for hormone monitoring. 

Artificial insemination can be performed: 

  • Natural Cycle: We monitor the woman’s own cycle, without hormonal medication, taking advantage of natural hormones.
  • Ovarian stimulation: Alternatively, the woman can receive hormonal medication (gonadotropins) to stimulate the production of follicles in the ovaries in a very controlled way, increasing chances of success.

Ovulation Induction: Once the follicles reach the right size and the endometrium has favourable characteristics, an injection of hCG (human chorionic gonadotropin) is administered to trigger ovulation.

Donor Sperm Preparation: Thawing and capacitation: Donor sperm, which has been frozen, is thawed and capacitated in the laboratory to concentrate the most motile sperm. 

Insemination: Insemination procedure: Introduction of the capacitated sperm into the woman’s uterus by means of a catheter. This procedure is simple and is carried out in the doctor’s office.

Procedure
03 Post-insemination

Short rest: The patient remains at rest for a few minutes after insemination.

Pregnancy Test: Approximately 14 days after insemination, a pregnancy test is performed to determine whether the procedure has been successful.

Artificial insemination with donor sperm (AID) is an assisted reproduction procedure in which donor sperm is introduced into the woman’s uterus.

WHO IS IT FOR?

This procedure is ideal for women facing single motherhood, couples of women or heterosexual couples where the man has severe fertility problems and we must resort to donor sperm. 

We recommend DAI in women under 38 years of age as the success rate decreases with age.

SUCCESS RATES

According to the statistical data for the 2020-2024 period from our centre, the overall clinical pregnancy rate per artificial insemination cycle with donor sperm was 25%. This rate was 29% in women aged 35 or under, 16.9% in those aged 36 to 39, and 11% in women aged 40 or over.

FAQs

The insemination procedure is generally painless, although some women may experience mild discomfort similar to that of a Pap smear.

Risks are minimal. There may be a risk of multiple pregnancy if ovarian stimulation medication has been used. Your doctor will explain this to you if you undergo this type of treatment. 

The average duration of treatment is approximately 30 days, from the start of ovarian stimulation or monitoring of the onset of the natural cycle to the pregnancy test.

Several insemination cycles are commonly needed to achieve pregnancy. A minimum of 2-3 cycles (up to a maximum of 4) is recommended before considering other fertility treatments.

The sperm donor is selected from a sperm bank. The choice is made based on the recipient’s physical characteristics, blood type and other factors such as genetic matching. Donors undergo rigorous medical, psychological and genetic screening.

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